AI tools differentiated by specific applications

Flo­ri­an De Vuyst is a uni­ver­si­ty pro­fes­sor spe­cial­iz­ing in applied math­e­mat­ics and a research sci­en­tist at the Bio­me­chan­ics and Bio­engi­neer­ing Lab­o­ra­to­ry (UTC-CNRS-BMBI). He explains the dif­fer­ent mod­els of arti­fi­cial intel­li­gence (AI).

Among the most wide­ly used AI mod­els are deep neur­al net­works. “These mod­els have the advan­tage of estab­lish­ing a pre­cise rela­tion­ship between input and out­put data. How­ev­er, the learn­ing phase requires a large vol­ume of data (mea­sure­ments, obser­va­tions, sim­u­la­tion results, con­tex­tu­al data…) and demands sig­nif­i­cant com­put­ing resources. This type of AI can be used to bet­ter under­stand the func­tion­ing of com­plex exper­i­men­tal devices where sev­er­al physics are involved. Neur­al net­works are capa­ble of repro­duc­ing the gen­er­al behav­iour of mul­ti-physics sys­tems and enable sen­si­tiv­i­ty and opti­miza­tion stud­ies to be car­ried out on oper­at­ing para­me­ters”, he explains. In col­lab­o­ra­tion with Tim­o­th­ée Baud­e­quin, the lab­o­ra­to­ry is plan­ning to use deep neur­al net­works to pre­dict the behav­iour of elec­tro­spin­ning devices. “These are machines that pro­duce nanofi­bres to make scaf­folds for cell cul­tures”, he says.

Oth­er AI mod­els used at UTC-CNRS-BMBI also include sta­tis­ti­cal learn­ing or machine learn­ing. “Mem­bers of the Char­ac­ter­i­za­tion and Per­son­al­ized Mod­el­ling of the Mus­cu­loskele­tal Sys­tem (C2MUST) team use this type of mod­el to deter­mine the behav­iour of mus­cu­loskele­tal sys­tems and, for exam­ple, pre­dict aging. It’s a prob­a­bilis­tic approach that takes account of uncer­tain­ties in mod­els, data or exper­i­men­tal con­di­tions”, stress­es Flo­ri­an De Vuyst.

Oth­er AI tools are ded­i­cat­ed to assist­ing image pro­cess­ing, enabling the detec­tion of anom­alies or the search for impor­tant fea­tures in images, not nec­es­sar­i­ly vis­i­ble to the human eye. “These can be sta­t­ic images or videos, but also dynam­ic 3D or even 4D images. This is one of Isabelle Claude’s areas of research, as she super­vised Abdel­ha­di Essam­lal­i’s the­sis on bile duct recon­struc­tion. It’s a patient-spe­cif­ic approach, where the patien­t’s organ is recon­struct­ed in vol­ume to help the prac­ti­tion­er pre­pare for surgery,” he adds.

It is often the appli­ca­tion that deter­mines the devel­op­ment of a par­tic­u­lar type of AI. “Take, for instance the case of deter­min­ing the mechan­i­cal behav­iour of liv­ing tis­sue. Usu­al­ly, we define one or more laws and try to find the one that best repro­duces exper­i­men­tal mea­sure­ments. Now, we use AI tech­niques in which we inte­grate these empir­i­cal laws into a fam­i­ly of more gen­er­al laws, and the neur­al net­work finds the sub-fam­i­ly and coef­fi­cients that are clos­est to real­i­ty. In a way, it’s a gen­er­al inte­grat­ed approach that enables us to be more gen­er­al­ist and more pre­cise when mod­el­ling a bio­log­i­cal tis­sue”, he explains.

Final­ly and more recent­ly, AI has been used to accel­er­ate numer­i­cal sim­u­la­tions of mechan­i­cal mod­els. “These include, for exam­ple, physics informed neur­al net­works, which have the advan­tage of being more gen­er­al and faster than con­ven­tion­al solvers such as finite ele­ment meth­ods. In the learn­ing phase of neur­al net­works, a so-called loss func­tion is used. In a PINN, the loss func­tion is an equa­tion residue. The prob­lem is solved when the loss reach­es zero,” he explains.

Today, AI mod­els are used in most fields. Nev­er­the­less, a cer­tain amount of vig­i­lance is still required with regard to pos­si­ble bias­es. “AI should be seen as an assis­tant which, par­tic­u­lar­ly in the bio­med­ical field, can pro­vide a com­ple­men­tary analy­sis or diag­no­sis that must imper­a­tive­ly be val­i­dat­ed by human prac­ti­tion­ers”, con­cludes Flo­ri­an De Vuyst.

MSD

Le magazine

Avril 2025 - N°65

Biomécanique pour la santé : des modèles d’intelligence artificielle spécifiques

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